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A. Beekman

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Review Open access Aug 2026

Protein–protein interaction inhibitors in the human proteome: lessons from 117 targeted interactions

A framework for accelerating the development of next-generation PPI therapeutics is provided by connecting interface architecture with optimal inhibitor modality and discovery strategy, revealing clear links between interface topology and inhibitor discovery strategies.

Ellie Hyde, A. Beekman · 0 citations

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