Review
Open access
Aug 2026
Protein–protein interaction inhibitors in the human proteome: lessons from 117 targeted interactions
A framework for accelerating the development of next-generation PPI therapeutics is provided by connecting interface architecture with optimal inhibitor modality and discovery strategy, revealing clear links between interface topology and inhibitor discovery strategies.
Ellie Hyde, A. Beekman
· RSC Medicinal Chemistry · 0 citations