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A. Bartko

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Open access Sep 2026

Five-country analysis of geographic and dietary drivers of gut microbiome composition and genomic variation

Human diet and lifestyle vary widely across cultures, shaping global diversity in gut microbiome composition and function. However, comparable cross-population studies have been limited by methodological heterogeneity. The Human Diets and Microbiome Initiative (THDMI) integrates standardized recruitment, dietary asse...

Lora Khatib, Renee E. Oles, Alejandra Ríos Hernández et al. · 0 citations
Conference Open access Aug 2026

Prediction and Entropy of Evolving Sequences: A Transformer-Based Estimator of Functional Information

It is demonstrated that transformer derived surprisal systematically distinguishes functionally constrained sequences from unconstrained ones across digital and biological substrates, establishing transformer surprisal as a potential measure of functional information in evolving systems.

Tyler D. Myers, Se-Jin Song, A. Bartko · 0 citations
Open access Aug 2026

Spatial transcriptomics reveals site-specific cellular and metabolic heterogeneity in bladder carcinoma in situ

Bladder carcinoma in situ (CIS) is a multifocal, non–muscle-invasive disease with a high risk of progression to muscle-invasive cancer. Current management strategies are often guided by genomic profiling of single tumor samples, which incompletely capture tumor heterogeneity and may contribute to treatment failure. In...

Tyler D. Myers, A. Salmasi, M. Meagher et al. · 0 citations
Open access Aug 2026

Joint-RPCA: domain-aware multi-omics integration for systems microbiology.

Joint Robust Principal Component Analysis (Joint-RPCA), a method designed with these statistical properties in mind and broadly applicable to multi-omics settings with similar challenges, reveals replicable and interpretable multi-omic patterns.

Bianca Cordazzo Vargas, C. Martino, A. Dilmore et al. · 1 citation

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