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Open access Sep 2026

Bevacizumab-Functionalized Exosome-Associated Chitosan Nanocomposite for Temozolomide Delivery and Apoptosis-Related Transcriptional Modulation in Experimental Glioma

Introduction Glioblastoma (GBM) has a poor prognosis, and temozolomide (TMZ) therapy is limited by a short half-life and insufficient intratumoral availability. We developed a bevacizumab (BVZ)-functionalized, exosome-associated chitosan nanocomposite loaded with TMZ (BVZ–Exo@CS–TMZ) as a multifunctional biohybrid plat...

Parvin Pourmasoumi, Farshid Zamani, Mohammad Bayat et al. · 0 citations
Sep 2026

Hepatoprotective effects of cinnamic acid against carbon tetrachloride–induced liver injury in a mouse model

Cinnamic acid may exert hepatoprotective effects against CCl₄-induced liver injury, with secondary favorable effects on renal biochemical markers of CCl₄-induced systemic toxicity, by modulating oxidative and inflammatory pathways.

Samira Nomiri, Reyhaneh Taebi, Yaser Mohammadi et al. · 0 citations

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