Author

A. Algeciras-Schimnich

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Open access Aug 2026

Optimized plasma p‐tau217 and p‐tau217/Aβ42 cutoffs enhance detection of pre‐clinical Alzheimer's disease across diverse participants

Plasma p‐tau217 and p‐tau217/Aβ42 reliably identify non‐Hispanic White individuals with symptomatic and pre‐clinical AD. However, performance across ethnoracially diverse groups remains unknown.

Y. Piura, P. Aduen, Leah Schecter et al. · Alzheimer's & Dementia · 0 citations

Open access Jul 2026

Targeted proteomics of postmortem human brain reveals neurobiologic heterogeneity in Alzheimer’s disease using NULISA technology

Proteomic differences in synapse integrity, tau post-translational modification, and ubiquitination associated with age at symptomatic onset and corticolimbic distribution of tangle pathology are observed.

S. R. Dunlop, Sarah J. Lincoln, Zhongwei Peng et al. · bioRxiv · 0 citations