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Author

A. J. Aguirre

2 papers indexed here

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Open access Oct 2026

Quantitative gene-level inference of tumor transcription from plasma epigenomes

Abstract Tumor phenotype and therapeutic vulnerability are shaped by dynamic transcriptional states that are not captured by genetic profiling alone and are difficult to monitor longitudinally. Existing plasma-based approaches have largely been developed using samples with high circulating tumor DNA fractions, evaluate...

M. Freedman, G. Gulati, D. Vasseur et al. · 0 citations
Open access Aug 2026

Multimodal Machine Learning for Predicting Outcomes in the PASS-01 Trial of Systemic Therapy for Metastatic Pancreatic Cancer

MULTIPL demonstrated robust prognostic performance in external validation, identified a subgroup enriched for benefit from GNP, and enabled discovery and validation of prognostic biomarkers in metastatic PDAC, underscoring the value of the PASS-01 Challenge.

W. Quan, D. Henault, A. Zhang et al. · 0 citations

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