A. A. van de Loosdrecht

The immunophenotypic landscape of newly diagnosed acute myeloid leukemia: Associations with genotype and outcomes

Summary Despite widespread immunophenotyping in acute myeloid leukemia (AML), its immunophenotypic heterogeneity remains incompletely understood. Here, we applied state-of-the-art computational modeling to >50 million single cells from diagnostic bone marrow aspirates of 502 AML patients. Jointly modeling leukemic and...